Brain Injury-Induced Synaptic Reorganization in Hilar Inhibitory Neurons Is Differentially Suppressed by Rapamycin

Following traumatic brain injury (TBI), treatment with rapamycin suppresses mammalian (mechanistic) target of rapamycin (mTOR) activity and specific components of hippocampal synaptic reorganization associated with altered cortical excitability and seizure susceptibility. Reemergence of seizures aft...

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Publicat a:eNeuro
Autors principals: Butler, Corwin R., Boychuk, Jeffery A., Smith, Bret N.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2017
Matèries:
New Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659239/
https://ncbi.nlm.nih.gov/pubmed/29085896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0134-17.2017
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