Effects of Rapamycin Treatment on Neurogenesis and Synaptic Reorganization in the Dentate Gyrus after Controlled Cortical Impact Injury in Mice

Post-traumatic epilepsy (PTE) is one consequence of traumatic brain injury (TBI). A prominent cell signaling pathway activated in animal models of both TBI and epilepsy is the mammalian target of rapamycin (mTOR). Inhibition of mTOR with rapamycin has shown promise as a potential modulator of epilep...

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Bibliografiska uppgifter
I publikationen:Front Syst Neurosci
Huvudupphovsmän: Butler, Corwin R., Boychuk, Jeffery A., Smith, Bret N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2015
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661228/
https://ncbi.nlm.nih.gov/pubmed/26640431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsys.2015.00163
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