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Gene Trap Mutagenesis in the Mouse
Gene trapping in mouse embryonic stem (ES) cells is an efficient method for the mutagenesis of the mammalian genome. Insertion of a gene trap vector disrupts gene function, reports gene expression, and provides a convenient tag for the identification of the insertion site. The trap vector can be del...
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| Publicat a: | Methods Enzymol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5659187/ https://ncbi.nlm.nih.gov/pubmed/20699145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0076-6879(10)77013-0 |
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