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Gene Trap Mutagenesis in the Mouse

Gene trapping in mouse embryonic stem (ES) cells is an efficient method for the mutagenesis of the mammalian genome. Insertion of a gene trap vector disrupts gene function, reports gene expression, and provides a convenient tag for the identification of the insertion site. The trap vector can be del...

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Publicat a:Methods Enzymol
Autors principals: Friedel, Roland H., Soriano, Philippe
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659187/
https://ncbi.nlm.nih.gov/pubmed/20699145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0076-6879(10)77013-0
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