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Sirtinol regulates the balance of Th17/Treg to prevent allograft rejection

BACKGROUND: Current immunosuppressive medications used after transplantation induce significant toxicity , and a new medication regimen is needed. Based on recent research, Sirt1 exerts a proinflammatory effect on the immune response. Sirtinol is a Sirt1 inhibitor, but its impact on allograft reject...

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Publicado en:Cell Biosci
Autores principales: Ye, Qing, Zhang, Mingjian, Wang, Yang, Fu, Shangxi, Han, Shu, Wang, Liming, Wang, Quanxing
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658927/
https://ncbi.nlm.nih.gov/pubmed/29090089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-017-0182-2
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