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The imbalance between Treg and Th17 cells caused by FTY720 treatment in skin allograft rejection
OBJECTIVES: FTY720 modulates CD4(+)T cells by the augmentation of regulatory T cell activity, secretion of suppressive cytokines and suppression of IL-17 secretion by Th17 cells. To further understand the process of graft rejection/acceptance, we evaluated skin allograft survival and associated even...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3400173/ https://ncbi.nlm.nih.gov/pubmed/22892927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6061/clinics/2012(07)17 |
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