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Discovery of Heteroaromatic Sulfones As a New Class of Biologically Compatible Thiol-Selective Reagents
The selective reaction of chemical reagents with reduced protein thiols is critical to biological research. This reaction is utilized to prevent cross-linking of cysteine-containing peptides in common proteomics workflows and is applied widely in discovery and targeted redox investigations of the me...
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| Izdano u: | ACS Chem Biol |
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| Glavni autori: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5658784/ https://ncbi.nlm.nih.gov/pubmed/28687042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00444 |
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