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Facile Amide Formation via S-Nitrosothioacids
[Image: see text] Here we report a novel amide bond formation strategy from simple thioacid and amine starting materials. The reaction is mediated by unstable, but very reactive S-nitroso thioacid intermediates. This fast reaction under mild conditions should be useful in synthesis.
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3045635/ https://ncbi.nlm.nih.gov/pubmed/21271725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol1031393 |
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