Neutralization of Zika virus by germline-like human monoclonal antibodies targeting cryptic epitopes on envelope domain III

The Zika virus (ZIKV), a flavivirus transmitted by Aedes mosquitoes, has emerged as a global public health concern. Pre-existing cross-reactive antibodies against other flaviviruses could modulate immune responses to ZIKV infection by antibody-dependent enhancement, highlighting the importance of un...

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Vydáno v:Emerg Microbes Infect
Hlavní autoři: Wu, Yanling, Li, Shun, Du, Lanying, Wang, Chunyu, Zou, Peng, Hong, Binbin, Yuan, Mengjiao, Ren, Xiaonan, Tai, Wanbo, Kong, Yu, Zhou, Chen, Lu, Lu, Zhou, Xiaohui, Jiang, Shibo, Ying, Tianlei
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658772/
https://ncbi.nlm.nih.gov/pubmed/29018252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emi.2017.79
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