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Parallel mapping with site-directed hydroxyl radicals and micrococcal nuclease reveals structural features of positioned nucleosomes in vivo

Micrococcal nuclease (MNase) has been widely used for analyses of nucleosome locations in many organisms. However, due to its sequence preference, the interpretations of the positions and occupancies of nucleosomes using MNase have remained controversial. Next-generation sequencing (NGS) has also be...

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Publicado en:PLoS One
Main Authors: Fuse, Tomohiro, Katsumata, Koji, Morohoshi, Koya, Mukai, Yukio, Ichikawa, Yuichi, Kurumizaka, Hitoshi, Yanagida, Akio, Urano, Takeshi, Kato, Hiroaki, Shimizu, Mitsuhiro
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658119/
https://ncbi.nlm.nih.gov/pubmed/29073207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186974
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