The Effect of Micrococcal Nuclease Digestion on Nucleosome Positioning Data

Eukaryotic genomes are packed into chromatin, whose basic repeating unit is the nucleosome. Nucleosome positioning is a widely researched area. A common experimental procedure to determine nucleosome positions involves the use of micrococcal nuclease (MNase). Here, we show that the cutting preferenc...

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Detalhes bibliográficos
Main Authors: Chung, Ho-Ryun, Dunkel, Ilona, Heise, Franziska, Linke, Christian, Krobitsch, Sylvia, Ehrenhofer-Murray, Ann E., Sperling, Silke R., Vingron, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012088/
https://ncbi.nlm.nih.gov/pubmed/21206756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015754
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