Parallel mapping with site-directed hydroxyl radicals and micrococcal nuclease reveals structural features of positioned nucleosomes in vivo

Micrococcal nuclease (MNase) has been widely used for analyses of nucleosome locations in many organisms. However, due to its sequence preference, the interpretations of the positions and occupancies of nucleosomes using MNase have remained controversial. Next-generation sequencing (NGS) has also be...

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Udgivet i:PLoS One
Main Authors: Fuse, Tomohiro, Katsumata, Koji, Morohoshi, Koya, Mukai, Yukio, Ichikawa, Yuichi, Kurumizaka, Hitoshi, Yanagida, Akio, Urano, Takeshi, Kato, Hiroaki, Shimizu, Mitsuhiro
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658119/
https://ncbi.nlm.nih.gov/pubmed/29073207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186974
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