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Uncoupling of dynamin polymerization and GTPase activity revealed by the conformation-specific nanobody dynab
Dynamin is a large GTPase that forms a helical collar at the neck of endocytic pits, and catalyzes membrane fission (Schmid and Frolov, 2011; Ferguson and De Camilli, 2012). Dynamin fission reaction is strictly dependent on GTP hydrolysis, but how fission is mediated is still debated (Antonny et al....
Shranjeno v:
| izdano v: | eLife |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
eLife Sciences Publications, Ltd
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5658065/ https://ncbi.nlm.nih.gov/pubmed/29022874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25197 |
| Oznake: |
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