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Activated protein C attenuates severe inflammation by targeting VLA-3(high) neutrophil subpopulation in mice

The host injury involved in multi-organ system failure during severe inflammation is mediated, in part, by massive infiltration and sequestration of hyperactive neutrophils in the visceral organ. A recombinant form of human activated protein C (rhAPC) has shown cyto-protective and anti-inflammatory...

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Bibliografski detalji
Izdano u:J Immunol
Glavni autori: Sarangi, Pranita P., Lee, Hyun-wook, Lerman, Yelena V., Trzeciak, Alissa, Harrower, Eric J., Rezaie, Alireza R., Kim, Minsoo
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658029/
https://ncbi.nlm.nih.gov/pubmed/28877991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700541
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