Sepsis lethality via exacerbated tissue infiltration and TLR-induced cytokine production by neutrophils is integrin α(3)β(1)-dependent

Integrin-mediated migration of neutrophils to infected tissue sites is vital for pathogen clearance and therefore host survival. Although β(2) integrins have been shown to mediate neutrophil transendothelial migration during systemic and local inflammation, relatively little information is available...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Lerman, Yelena V., Lim, Kihong, Hyun, Young-Min, Falkner, Kathleen L., Yang, Hongmei, Pietropaoli, Anthony P., Sonnenberg, Arnoud, Sarangi, Pranita P., Kim, Minsoo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Plenary Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256905/
https://ncbi.nlm.nih.gov/pubmed/25278585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-01-552943
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