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Activated protein C attenuates severe inflammation by targeting VLA-3(high) neutrophil subpopulation in mice
The host injury involved in multi-organ system failure during severe inflammation is mediated, in part, by massive infiltration and sequestration of hyperactive neutrophils in the visceral organ. A recombinant form of human activated protein C (rhAPC) has shown cyto-protective and anti-inflammatory...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5658029/ https://ncbi.nlm.nih.gov/pubmed/28877991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700541 |
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