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Role of G-proteins in islet function in health and diabetes

Glucose-stimulated insulin secretion [GSIS] involves interplay between metabolic and cationic events. Seminal contributions from multiple laboratories affirm essential roles for small G-proteins [Rac1, Cdc42, Arf6, Rab27A] in GSIS. Activation of these signaling proteins promotes cytoskeletal remodel...

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Bibliografske podrobnosti
izdano v:Diabetes Obes Metab
Glavni avtor: Kowluru, Anjaneyulu
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657296/
https://ncbi.nlm.nih.gov/pubmed/28880478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.13011
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