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Role of G-proteins in islet function in health and diabetes

Glucose-stimulated insulin secretion [GSIS] involves interplay between metabolic and cationic events. Seminal contributions from multiple laboratories affirm essential roles for small G-proteins [Rac1, Cdc42, Arf6, Rab27A] in GSIS. Activation of these signaling proteins promotes cytoskeletal remodel...

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Bibliografiske detaljer
Udgivet i:Diabetes Obes Metab
Hovedforfatter: Kowluru, Anjaneyulu
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657296/
https://ncbi.nlm.nih.gov/pubmed/28880478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.13011
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