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Histone deacetylase inhibitors containing a benzamide functional group and a pyridyl cap are preferentially effective human immunodeficiency virus-1 latency-reversing agents in primary resting CD4(+) T cells

Antiretroviral therapy (ART) can control human immunodeficiency virus-1 (HIV-1) replication in infected individuals. Unfortunately, patients remain persistently infected owing to the establishment of latent infection requiring that ART be maintained indefinitely. One strategy being pursued involves...

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Detalhes bibliográficos
Publicado no:J Gen Virol
Main Authors: Kobayashi, Yoshifumi, Gélinas, Céline, Dougherty, Joseph P.
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657027/
https://ncbi.nlm.nih.gov/pubmed/28113052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000716
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