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Practical Recommendations for Therapeutic Drug Monitoring of Kinase Inhibitors in Oncology

Despite the fact that pharmacokinetic exposure of kinase inhibitors (KIs) is highly variable and clear relationships exist between exposure and treatment outcomes, fixed dosing is still standard practice. This review aims to summarize the available clinical pharmacokinetic and pharmacodynamic data i...

詳細記述

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書誌詳細
出版年:Clin Pharmacol Ther
主要な著者: Verheijen, Remy B., Yu, Huixin, Schellens, Jan H.M., Beijnen, Jos H., Steeghs, Neeltje, Huitema, Alwin D.R.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656880/
https://ncbi.nlm.nih.gov/pubmed/28699160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.787
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