Therapeutic drug monitoring of small molecule kinase inhibitors in oncology in a real‐world cohort study: does age matter?

AIM: Pharmacokinetics of small molecule kinase inhibitors (KIs) used in cancer treatment may alter with increasing age, but results are conflicting. This study aims to compare exposure to KIs between older and younger patients (≥70 and <70 years) in clinical practice. METHODS: KI plasma concentra...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Crombag, Marie‐Rose B.S., van Doremalen, Jacobine G.C., Janssen, Julie M., Rosing, Hilde, Schellens, Jan H.M., Beijnen, Jos H., Steeghs, Neeltje, Huitema, Alwin D.R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6256014/
https://ncbi.nlm.nih.gov/pubmed/30068020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13725
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