Melatonin ameliorates hypoglycemic stress‐induced brain endothelial tight junction injury by inhibiting protein nitration of TP53‐induced glycolysis and apoptosis regulator

Severe hypoglycemia has a detrimental impact on the cerebrovasculature, but the molecular events that lead to the disruption of the integrity of the tight junctions remain unclear. Here, we report that the microvessel integrity was dramatically compromised (59.41% of wild‐type mice) in TP53‐induced...

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Detalhes bibliográficos
Publicado no:J Pineal Res
Main Authors: Wang, Cheng‐kun, Ahmed, Muhammad Masood, Jiang, Quan, Lu, Nan‐nan, Tan, Chao, Gao, Yin‐ping, Mahmood, Qaisar, Chen, Dan‐yang, Fukunaga, Kohji, Li, Mei, Chen, Zhong, Wilcox, Christopher S., Lu, Ying‐mei, Qin, Zheng‐hong, Han, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656838/
https://ncbi.nlm.nih.gov/pubmed/28776759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jpi.12440
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