Melatonin ameliorates hypoglycemic stress‐induced brain endothelial tight junction injury by inhibiting protein nitration of TP53‐induced glycolysis and apoptosis regulator

Severe hypoglycemia has a detrimental impact on the cerebrovasculature, but the molecular events that lead to the disruption of the integrity of the tight junctions remain unclear. Here, we report that the microvessel integrity was dramatically compromised (59.41% of wild‐type mice) in TP53‐induced...

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Detaylı Bibliyografya
Yayımlandı:J Pineal Res
Asıl Yazarlar: Wang, Cheng‐kun, Ahmed, Muhammad Masood, Jiang, Quan, Lu, Nan‐nan, Tan, Chao, Gao, Yin‐ping, Mahmood, Qaisar, Chen, Dan‐yang, Fukunaga, Kohji, Li, Mei, Chen, Zhong, Wilcox, Christopher S., Lu, Ying‐mei, Qin, Zheng‐hong, Han, Feng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656838/
https://ncbi.nlm.nih.gov/pubmed/28776759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jpi.12440
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