Chargement en cours...
Distinct activation mechanisms trigger the trypanocidal activity of DNA damaging prodrugs
Quinone‐based compounds have been exploited to treat infectious diseases and cancer, with such chemicals often functioning as inhibitors of key metabolic pathways or as prodrugs. Here, we screened an aziridinyl 1,4‐benzoquinone (ABQ) library against the causative agents of trypanosomiasis, and cutan...
Enregistré dans:
| Publié dans: | Mol Microbiol |
|---|---|
| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2017
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5656836/ https://ncbi.nlm.nih.gov/pubmed/28792090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13767 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|