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Prion disease pathogenesis in the absence of the commensal microbiota

Prion diseases are a unique group of transmissible, typically sub-acute, neurodegenerative disorders. During central nervous system (CNS) prion disease, the microglia become activated and are thought to provide a protective response by scavenging and clearing prions. The mammalian intestine is host...

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Bibliographische Detailangaben
Veröffentlicht in:J Gen Virol
Hauptverfasser: Bradford, Barry M., Tetlow, Laura, Mabbott, Neil A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Microbiology Society 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656778/
https://ncbi.nlm.nih.gov/pubmed/28708055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000860
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