Escaping Host Factor PI4KB Inhibition: Enterovirus Genomic RNA Replication in the Absence of Replication Organelles

Enteroviruses reorganize cellular endomembranes into replication organelles (ROs) for genome replication. Although enterovirus replication depends on phosphatidylinositol 4-kinase type IIIβ (PI4KB), its role, and that of its product, phosphatidylinositol 4-phosphate (PI4P), is only partially underst...

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Publicado en:Cell Rep
Main Authors: Melia, Charlotte E., van der Schaar, Hilde M., Lyoo, Heyrhyoung, Limpens, Ronald W.A.L., Feng, Qian, Wahedi, Maryam, Overheul, Gijs J., van Rij, Ronald P., Snijder, Eric J., Koster, Abraham J., Bárcena, Montserrat, van Kuppeveld, Frank J.M.
Formato: Artigo
Idioma:Inglês
Publicado: The Authors. 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656745/
https://ncbi.nlm.nih.gov/pubmed/29045829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.068
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