Escaping Host Factor PI4KB Inhibition: Enterovirus Genomic RNA Replication in the Absence of Replication Organelles

Enteroviruses reorganize cellular endomembranes into replication organelles (ROs) for genome replication. Although enterovirus replication depends on phosphatidylinositol 4-kinase type IIIβ (PI4KB), its role, and that of its product, phosphatidylinositol 4-phosphate (PI4P), is only partially underst...

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Pubblicato in:Cell Rep
Autori principali: Melia, Charlotte E., van der Schaar, Hilde M., Lyoo, Heyrhyoung, Limpens, Ronald W.A.L., Feng, Qian, Wahedi, Maryam, Overheul, Gijs J., van Rij, Ronald P., Snijder, Eric J., Koster, Abraham J., Bárcena, Montserrat, van Kuppeveld, Frank J.M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Authors. 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656745/
https://ncbi.nlm.nih.gov/pubmed/29045829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.068
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