Gamma frequency entrainment attenuates amyloid load and modifies microglia

Changes in gamma oscillations (20-50 Hz) have been observed in several neurological disorders. However, the relationship between gamma and cellular pathologies is unclear. Here, we show reduced behaviorally-driven gamma before the onset of plaque formation or cognitive decline in a mouse model of Al...

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Pubblicato in:Nature
Autori principali: Iaccarino, Hannah F., Singer, Annabelle C., Martorell, Anthony J., Rudenko, Andrii, Gao, Fan, Gillingham, Tyler Z., Mathys, Hansruedi, Seo, Jinsoo, Kritskiy, Oleg, Abdurrob, Fatema, Adaikkan, Chinnakkaruppan, Canter, Rebecca G., Rueda, Richard, Brown, Emery N., Boyden, Edward S., Tsai, Li-Huei
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656389/
https://ncbi.nlm.nih.gov/pubmed/27929004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20587
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