Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution

Microglia, the tissue-resident macrophages in the brain, are damage sensors that react to nearly any perturbation, including neurodegenerative diseases such as Alzheimer’s disease (AD). Here, using single-cell RNA sequencing, we determined the transcriptome of more than 1,600 individual microglia ce...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Mathys, Hansruedi, Adaikkan, Chinnakkaruppan, Gao, Fan, Young, Jennie Z., Manet, Elodie, Hemberg, Martin, De Jager, Philip L., Ransohoff, Richard M., Regev, Aviv, Tsai, Li-Huei
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642107/
https://ncbi.nlm.nih.gov/pubmed/29020624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.039
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