Gamma frequency entrainment attenuates amyloid load and modifies microglia

Changes in gamma oscillations (20-50 Hz) have been observed in several neurological disorders. However, the relationship between gamma and cellular pathologies is unclear. Here, we show reduced behaviorally-driven gamma before the onset of plaque formation or cognitive decline in a mouse model of Al...

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Détails bibliographiques
Publié dans:Nature
Auteurs principaux: Iaccarino, Hannah F., Singer, Annabelle C., Martorell, Anthony J., Rudenko, Andrii, Gao, Fan, Gillingham, Tyler Z., Mathys, Hansruedi, Seo, Jinsoo, Kritskiy, Oleg, Abdurrob, Fatema, Adaikkan, Chinnakkaruppan, Canter, Rebecca G., Rueda, Richard, Brown, Emery N., Boyden, Edward S., Tsai, Li-Huei
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656389/
https://ncbi.nlm.nih.gov/pubmed/27929004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20587
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