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A method for allocating low-coverage sequencing resources by targeting haplotypes rather than individuals

BACKGROUND: This paper describes a heuristic method for allocating low-coverage sequencing resources by targeting haplotypes rather than individuals. Low-coverage sequencing assembles high-coverage sequence information for every individual by accumulating data from the genome segments that they shar...

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Foilsithe in:Genet Sel Evol
Main Authors: Ros-Freixedes, Roger, Gonen, Serap, Gorjanc, Gregor, Hickey, John M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655873/
https://ncbi.nlm.nih.gov/pubmed/29070022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12711-017-0353-y
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