A conserved C-terminal RXG motif in the NgBR subunit of cis-prenyltransferase is critical for prenyltransferase activity

cis-Prenyltransferases (cis-PTs) constitute a large family of enzymes conserved during evolution and present in all domains of life. In eukaryotes and archaea, cis-PT is the first enzyme committed to the synthesis of dolichyl phosphate, an obligate lipid carrier in protein glycosylation reactions. T...

Full description

Saved in:
Bibliographic Details
Published in:J Biol Chem
Main Authors: Grabińska, Kariona A., Edani, Ban H., Park, Eon Joo, Kraehling, Jan R., Sessa, William C.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2017
Subjects:
Enzymology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655512/
https://ncbi.nlm.nih.gov/pubmed/28842490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.806034
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items