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Mutation of NgBR, a subunit of cis-prenyltransferase, causes a congenial disorder of glycosylation
Dolichol is an obligate carrier of glycans for N-linked protein glycosylation, O-mannosylation, and GPI anchor biosynthesis. Cis-prenyltransferase (cis-PTase) is the first enzyme committed to the synthesis of dolichol. However, the proteins responsible for mammalian cis-PTase activity have not been...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4161961/ https://ncbi.nlm.nih.gov/pubmed/25066056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.06.016 |
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