Identification of optineurin as an interleukin-1 receptor-associated kinase 1-binding protein and its role in regulation of MyD88-dependent signaling

Upon stimulation of toll-like receptors with various microbial ligands, induction of a variety of inflammatory genes is elicited by activation of a myeloid differentiation primary-response protein 88 (MyD88)-dependent signaling pathway. Interleukin-1 (IL-1) receptor-associated kinase 1 (IRAK1) plays...

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Vydáno v:J Biol Chem
Hlavní autoři: Tanishima, Mitsuyoshi, Takashima, Shigeo, Honda, Arata, Yasuda, Daisuke, Tanikawa, Takashi, Ishii, Satoshi, MaruYama, Takashi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655504/
https://ncbi.nlm.nih.gov/pubmed/28882891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.813899
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