Simple, mild, one-step labelling of proteins with gallium-68 using a tris(hydroxypyridinone) bifunctional chelator: a (68)Ga-THP-scFv targeting the prostate-specific membrane antigen

BACKGROUND: Labelling proteins with gallium-68 using bifunctional chelators is often problematic because of unsuitably harsh labelling conditions such as low pH or high temperature and may entail post-labelling purification. To determine whether tris(hydroxypyridinone) (THP) bifunctional chelators o...

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Bibliographische Detailangaben
Veröffentlicht in:EJNMMI Res
Hauptverfasser: Nawaz, Saima, Mullen, Gregory E. D., Sunassee, Kavitha, Bordoloi, Jayanta, Blower, Philip J., Ballinger, James R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2017
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655379/
https://ncbi.nlm.nih.gov/pubmed/29067565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-017-0336-6
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