Cell Type-Specific mRNA Dysregulation in Hippocampal CA1 Pyramidal Neurons of the Fragile X Syndrome Mouse Model

Fragile X syndrome (FXS) is a genetic disorder due to the silencing of the Fmr1 gene, causing intellectual disability, seizures, hyperactivity, and social anxiety. All these symptoms result from the loss of expression of the RNA binding protein fragile X mental retardation protein (FMRP), which alte...

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Dades bibliogràfiques
Publicat a:Front Mol Neurosci
Autors principals: Ceolin, Laura, Bouquier, Nathalie, Vitre-Boubaker, Jihane, Rialle, Stéphanie, Severac, Dany, Valjent, Emmanuel, Perroy, Julie, Puighermanal, Emma
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655025/
https://ncbi.nlm.nih.gov/pubmed/29104533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00340
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