Ribosomal Protein S6 Phosphorylation Is Involved in Novelty-Induced Locomotion, Synaptic Plasticity and mRNA Translation

The phosphorylation of the ribosomal protein S6 (rpS6) is widely used to track neuronal activity. Although it is generally assumed that rpS6 phosphorylation has a stimulatory effect on global protein synthesis in neurons, its exact biological function remains unknown. By using a phospho-deficient rp...

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Veröffentlicht in:Front Mol Neurosci
Hauptverfasser: Puighermanal, Emma, Biever, Anne, Pascoli, Vincent, Melser, Su, Pratlong, Marine, Cutando, Laura, Rialle, Stephanie, Severac, Dany, Boubaker-Vitre, Jihane, Meyuhas, Oded, Marsicano, Giovanni, Lüscher, Christian, Valjent, Emmanuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742586/
https://ncbi.nlm.nih.gov/pubmed/29311811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00419
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