Cell Type-Specific mRNA Dysregulation in Hippocampal CA1 Pyramidal Neurons of the Fragile X Syndrome Mouse Model

Fragile X syndrome (FXS) is a genetic disorder due to the silencing of the Fmr1 gene, causing intellectual disability, seizures, hyperactivity, and social anxiety. All these symptoms result from the loss of expression of the RNA binding protein fragile X mental retardation protein (FMRP), which alte...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Ceolin, Laura, Bouquier, Nathalie, Vitre-Boubaker, Jihane, Rialle, Stéphanie, Severac, Dany, Valjent, Emmanuel, Perroy, Julie, Puighermanal, Emma
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655025/
https://ncbi.nlm.nih.gov/pubmed/29104533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00340
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