Interleukin-7 Induces Osteoclast Formation via STAT5, Independent of Receptor Activator of NF-kappaB Ligand

Interleukin-7 (IL-7), which is required for the development and survival of T cells in the thymus and periphery, plays a role in joint destruction. However, it remains unclear how IL-7 affects osteoclast formation. Thus, we investigated the mechanism by which IL-7 induced osteoclast formation throug...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Kim, Jin-Hee, Sim, Ji Hyun, Lee, Sunkyung, Seol, Min A., Ye, Sang-Kyu, Shin, Hyun Mu, Lee, Eun Bong, Lee, Yun Jong, Choi, Yun Jung, Yoo, Wan-Hee, Kim, Jin Hyun, Kim, Wan-Uk, Lee, Dong-Sup, Kim, Jin-Hong, Kang, Insoo, Kang, Seong Wook, Kim, Hang-Rae
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655015/
https://ncbi.nlm.nih.gov/pubmed/29104576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01376
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