Piperlongumine Improves Lipopolysaccharide-Induced Amyloidogenesis by Suppressing NF-KappaB Pathway

Amyloidogenesis is known to cause Alzheimer’s disease. Our previous studies have found that lipopolysaccharide (LPS) causes neuroinflammation and amyloidogenesis through activation of nuclear factor kappaB (NF-κB). Piperlongumine (PL) is an alkaloid amide found naturally in long pepper (Piper longum...

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Detalhes bibliográficos
Publicado no:Neuromolecular Med
Main Authors: Gu, Sun Mi, Lee, Hee Pom, Ham, Young Wan, Son, Dong Ju, Kim, Hoi Yeong, Oh, Ki Wan, Han, Sang-Bae, Yun, Jaesuk, Hong, Jin Tae
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2018
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097046/
https://ncbi.nlm.nih.gov/pubmed/29802525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12017-018-8495-9
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