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‘Hotspots’ of Antigen Presentation Revealed by Human Leukocyte Antigen Ligandomics for Neoantigen Prioritization

The remarkable clinical efficacy of the immune checkpoint blockade therapies has motivated researchers to discover immunogenic epitopes and exploit them for personalized vaccines. Human leukocyte antigen (HLA)-binding peptides derived from processing and presentation of mutated proteins are one of t...

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Publicat a:Front Immunol
Autors principals: Müller, Markus, Gfeller, David, Coukos, George, Bassani-Sternberg, Michal
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654951/
https://ncbi.nlm.nih.gov/pubmed/29104575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01367
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