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‘Hotspots’ of Antigen Presentation Revealed by Human Leukocyte Antigen Ligandomics for Neoantigen Prioritization

The remarkable clinical efficacy of the immune checkpoint blockade therapies has motivated researchers to discover immunogenic epitopes and exploit them for personalized vaccines. Human leukocyte antigen (HLA)-binding peptides derived from processing and presentation of mutated proteins are one of t...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Müller, Markus, Gfeller, David, Coukos, George, Bassani-Sternberg, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654951/
https://ncbi.nlm.nih.gov/pubmed/29104575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01367
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