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ALK and IGF-1R as independent targets in crizotinib resistant lung cancer
ALK positive non-small cell lung cancer is highly responsive to ALK inhibitors such as crizotinib, but drug resistance typically develops within a year of treatment. In this study we investigated whether IGF-1R is an independent druggable target in ALK-positive lung cancer cells. We confirmed that c...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5654778/ https://ncbi.nlm.nih.gov/pubmed/29066738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14289-w |
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