Effects of crenolanib, a non-selective inhibitor of PDGFR, in a mouse model of transient middle cerebral artery occlusion

Neurogenesis in the subventricular zone (SVZ) plays a vital role in neurologic recovery after stroke. However, only a small fraction of newly generated neuroblasts from the SVZ will survive long-term. Successful migration and survival of neuroblasts requires angiogenesis, lesion-derived chemo-attrac...

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Publicat a:Neuroscience
Autors principals: Wang, Jianping, Fu, Xiaojie, Zhang, Di, Yu, Lie, Lu, Zhengfang, Gao, Yufeng, Liu, Xianliang, Man, Jiang, Li, Sijia, Li, Nan, Wang, Menghan, Liu, Xi, Chen, Xuemei, Zang, Weidong, Yang, Qingwu, Wang, Jian
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653447/
https://ncbi.nlm.nih.gov/pubmed/28943249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2017.09.025
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