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Expression of C/EBPβ in myeloid progenitors during sepsis promotes immunosuppression

Sepsis-induced myeloid-derived suppressor cells (MDSCs) contribute to immunosuppression associated with sepsis. We reported that the CCAAT enhancer-binding protein C/EBPβ activates microRNA (miR)-21 and miR-181b expressions, which induce transcription factor NFI-A to support the generation and expan...

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Détails bibliographiques
Publié dans:Mol Immunol
Auteurs principaux: Dai, Jun, Kumbhare, Ajinkya, Youssef, Dima, Yao, Zhi Q., McCall, Charles E., El Gazzar, Mohamed
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653439/
https://ncbi.nlm.nih.gov/pubmed/28934717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2017.09.008
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