Charge Detection Mass Spectrometry Identifies Preferred Non-Icosahedral Polymorphs in the Self-Assembly of Woodchuck Hepatitis Virus Capsids

Woodchuck hepatitis virus (WHV) is prone to aberrant assembly in vitro, and can form a broad distribution of oversized particles. Characterizing aberrant assembly products is challenging because they are both large and heterogeneous. In this work, charge detection mass spectrometry (CDMS) is used to...

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Udgivet i:J Mol Biol
Main Authors: Pierson, Elizabeth E., Keifer, David Z., Kukreja, Alexander A., Wang, Joseph C.-Y., Zlotnick, Adam, Jarrold, Martin F.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653371/
https://ncbi.nlm.nih.gov/pubmed/26151485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.06.019
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