Asymmetrizing an icosahedral virus capsid by hierarchical assembly of subunits with designed asymmetry

Symmetrical protein complexes are ubiquitous in biology. Many have been re-engineered for chemical and medical applications. Viral capsids and their assembly are frequent platforms for these investigations. A means to create asymmetric capsids may expand applications. Here, starting with homodimeric...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Zhao, Zhongchao, Wang, Joseph Che-Yen, Zhang, Mi, Lyktey, Nicholas A., Jarrold, Martin F., Jacobson, Stephen C., Zlotnick, Adam
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7838286/
https://ncbi.nlm.nih.gov/pubmed/33500404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20862-1
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg