Src SUMOylation Inhibits Tumor Growth Via Decreasing FAK Y925 Phosphorylation

Src, a non-receptor tyrosine kinase protein, plays a critical role in cell proliferation and tumorigenesis. SUMOylation, a reversible ubiquitination-like post-translational modification, is vital for tumor progression. Here, we report that the Src protein can be SUMOylated at lysine 318 both in vitr...

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Bibliografiske detaljer
Udgivet i:Neoplasia
Main Authors: Wang, Jing, Deng, Rong, Cui, Nan, Zhang, Hailong, Liu, Tianqi, Dou, Jinzhuo, Zhao, Xian, Chen, Ran, Wang, Yanli, Yu, Jianxiu, Huang, Jian
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press 2017
Fag:
Original article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653241/
https://ncbi.nlm.nih.gov/pubmed/29069627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.09.001
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