Inhibition of miR-142-5P ameliorates disease in mouse models of experimental colitis

BACKGROUND: MicroRNAs (miRNAs) are epigenetically involved in regulating gene expression. They may be of importance in the pathogenesis of inflammatory bowel disease (IBD). The aim of this study was to determine the role of miRNAs by their specific blocking in the CD4+CB45RB(hi) T-cell transfer mode...

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Publicat a:PLoS One
Autors principals: Duijvis, Nicolette W., Moerland, Perry D., Kunne, Cindy, Slaman, Monique M. W., van Dooren, Faas H., Vogels, Esther W., de Jonge, Wouter J., Meijer, Sybren L., Fluiter, Kees, te Velde, Anje A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653202/
https://ncbi.nlm.nih.gov/pubmed/29059189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185097
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