Deletion of eIF2β lysine stretches creates a dominant negative that affects the translation and proliferation in human cell line: A tool for arresting the cell growth

Background: Eukaryote initiation factor 2 subunit β (eIF2β) plays a crucial role in regulation protein synthesis, which mediates the interaction of eIF2 with mRNA. eIF2β contains evolutionarily conserved polylysine stretches in amino-terminal region and a zinc finger motif in the carboxy-terminus. M...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Salton, Gabrielle Dias, Laurino, Claudia Cilene Fernandes Correia, Mega, Nicolás Oliveira, Delgado-Cañedo, Andrés, Setterblad, Niclas, Carmagnat, Maryvonnick, Xavier, Ricardo Machado, Cirne-Lima, Elizabeth, Lenz, Guido, Henriques, João Antonio Pêgas, Laurino, Jomar Pereira
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653189/
https://ncbi.nlm.nih.gov/pubmed/28692326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1345383
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