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Ribosomes slide on lysine-encoding homopolymeric A stretches
Protein output from synonymous codons is thought to be equivalent if appropriate tRNAs are sufficiently abundant. Here we show that mRNAs encoding iterated lysine codons, AAA or AAG, differentially impact protein synthesis: insertion of iterated AAA codons into an ORF diminishes protein expression m...
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| 出版年: | eLife |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4363877/ https://ncbi.nlm.nih.gov/pubmed/25695637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05534 |
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